| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF97488.1 | ispB | AL538_06860 | AL538_11150 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.403 |
| AMF97488.1 | ubiA | AL538_06860 | AL538_08955 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.758 |
| AMF97488.1 | ubiD | AL538_06860 | AL538_09205 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family. | 0.929 |
| AMF97488.1 | ubiX | AL538_06860 | AL538_11100 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.918 |
| fbp | mpl | AL538_11090 | AL538_11095 | Fructose-bisphosphatase; Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.470 |
| fbp | ubiX | AL538_11090 | AL538_11100 | Fructose-bisphosphatase; Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.470 |
| ispB | AMF97488.1 | AL538_11150 | AL538_06860 | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.403 |
| ispB | ubiA | AL538_11150 | AL538_08955 | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.913 |
| ispB | ubiX | AL538_11150 | AL538_11100 | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.414 |
| ispE | ubiX | AL538_13255 | AL538_11100 | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.419 |
| mpl | fbp | AL538_11095 | AL538_11090 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Fructose-bisphosphatase; Catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. | 0.470 |
| mpl | tbpA | AL538_11095 | AL538_11105 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.499 |
| mpl | thiP | AL538_11095 | AL538_11110 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.437 |
| mpl | thiQ | AL538_11095 | AL538_11115 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Thiamine ABC transporter ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. | 0.437 |
| mpl | ubiX | AL538_11095 | AL538_11100 | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.846 |
| tbpA | mpl | AL538_11105 | AL538_11095 | Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.499 |
| tbpA | thiP | AL538_11105 | AL538_11110 | Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
| tbpA | thiQ | AL538_11105 | AL538_11115 | Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thiamine ABC transporter ATP-binding protein; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. | 0.957 |
| tbpA | ubiX | AL538_11105 | AL538_11100 | Thiamine ABC transporter substrate-binding protein; Part of the thiamine and TPP transport system tbpA-thiPQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aromatic acid decarboxylase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.499 |
| thiP | mpl | AL538_11110 | AL538_11095 | Permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.437 |