| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF96501.1 | yfiC | AL538_01500 | AL538_11875 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.499 |
| AMF98027.1 | AMF98829.1 | AL538_10120 | AL538_14480 | Hydrolase TatD; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| AMF98027.1 | yfiC | AL538_10120 | AL538_11875 | Hydrolase TatD; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.507 |
| AMF98364.1 | brnQ | AL538_11870 | AL538_11880 | ATP-dependent RNA helicase SrmB; Facilitates an early step in the assembly of the 50S subunit of the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. | Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids. | 0.605 |
| AMF98364.1 | yfiC | AL538_11870 | AL538_11875 | ATP-dependent RNA helicase SrmB; Facilitates an early step in the assembly of the 50S subunit of the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.737 |
| AMF98829.1 | AMF98027.1 | AL538_14480 | AL538_10120 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hydrolase TatD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| AMF98829.1 | yfiC | AL538_14480 | AL538_11875 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.437 |
| AMG00468.1 | yfiC | AL538_22565 | AL538_11875 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.499 |
| brnQ | AMF98364.1 | AL538_11880 | AL538_11870 | Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids. | ATP-dependent RNA helicase SrmB; Facilitates an early step in the assembly of the 50S subunit of the ribosome; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. | 0.605 |
| brnQ | lysS | AL538_11880 | AL538_11910 | Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids. | lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.478 |
| brnQ | yfiC | AL538_11880 | AL538_11875 | Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.699 |
| ffh | ftsY | AL538_06560 | AL538_08995 | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belo [...] | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.998 |
| ffh | yfiC | AL538_06560 | AL538_11875 | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belo [...] | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.415 |
| ftsY | ffh | AL538_08995 | AL538_06560 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belo [...] | 0.998 |
| ftsY | lysS | AL538_08995 | AL538_11910 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.553 |
| ftsY | yfiC | AL538_08995 | AL538_11875 | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.547 |
| lysS | brnQ | AL538_11910 | AL538_11880 | lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | Branched-chain amino acid transporter; Component of the transport system for branched-chain amino acids. | 0.478 |
| lysS | ftsY | AL538_11910 | AL538_08995 | lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.553 |
| lysS | yfiC | AL538_11910 | AL538_11875 | lysine--tRNA ligase; Class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.412 |
| rsmI | yfiC | AL538_11590 | AL538_11875 | Tetrapyrrole methylase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. | SAM-dependent methyltransferase; Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC). | 0.582 |