| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF97650.1 | AMF99628.1 | AL538_07880 | AL538_18040 | Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
| AMF99627.1 | AMF99628.1 | AL538_18035 | AL538_18040 | Aspartoacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.638 |
| AMF99628.1 | AMF97650.1 | AL538_18040 | AL538_07880 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bacterioferritin; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.497 |
| AMF99628.1 | AMF99627.1 | AL538_18040 | AL538_18035 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartoacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.638 |
| AMF99628.1 | RrtA | AL538_18040 | AL538_14280 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rhombosortase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.572 |
| AMF99628.1 | cysS | AL538_18040 | AL538_15860 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.526 |
| AMF99628.1 | folE | AL538_18040 | AL538_26095 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
| AMF99628.1 | hisE | AL538_18040 | AL538_15835 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.495 |
| AMF99628.1 | nrdG | AL538_18040 | AL538_24430 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.806 |
| AMF99628.1 | queC | AL538_18040 | AL538_17070 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.876 |
| AMF99628.1 | queE | AL538_18040 | AL538_17065 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.817 |
| AMF99628.1 | queF | AL538_18040 | AL538_12960 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.841 |
| RrtA | AMF99628.1 | AL538_14280 | AL538_18040 | Rhombosortase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.572 |
| cysS | AMF99628.1 | AL538_15860 | AL538_18040 | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.526 |
| cysS | hisE | AL538_15860 | AL538_15835 | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.548 |
| folE | AMF99628.1 | AL538_26095 | AL538_18040 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
| folE | hisE | AL538_26095 | AL538_15835 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.467 |
| folE | nrdG | AL538_26095 | AL538_24430 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
| folE | queC | AL538_26095 | AL538_17070 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.892 |
| folE | queE | AL538_26095 | AL538_17065 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-carboxy-7-deazaguanine synthase QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.834 |