Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMG00276.1N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)    
Predicted Functional Partners:
AMG00277.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
AMF98740.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
AMG00275.1
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
AMF98739.1
Deoxyribonuclease HsdR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.971
AMF98738.1
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.739
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.674
AMG00280.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.655
BrxC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.580
AMF98507.1
Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.545
AMG01446.1
Lipopolysaccharide modification acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.493
Your Current Organism:
Vibrio harveyi
NCBI taxonomy Id: 669
Other names: ATCC 14126, Achromobacter harveyi, Beneckea harveyi, Beneckea neptuna, CAIM 513, CCUG 28584, CECT 525, CIP 103192, DSM 19623, IFO 15634, LMG 4044, LMG:4044, Lucibacterium harveyi, NBRC 15634, NCCB 80033, NCTC 12970, Photobacterium harveyi, Pseudomonas harveyi, V. harveyi, Vibrio carchariae, Vibrio sp. HENC-01, Vibrio sp. HENC-02, Vibrio sp. PG 001, Vibrio sp. PG 002, Vibrio sp. PG 006, Vibrio sp. PG 007, Vibrio trachuri
Server load: low (22%) [HD]