| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMG00077.1 | mgsA | AL538_20450 | AL538_23035 | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.825 |
| birA | cca | AL538_08720 | AL538_11420 | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.758 |
| birA | coaE | AL538_08720 | AL538_06525 | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.639 |
| birA | dapB | AL538_08720 | AL538_11680 | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.736 |
| birA | mgsA | AL538_08720 | AL538_23035 | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.670 |
| birA | pcnB | AL538_08720 | AL538_06415 | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.800 |
| cca | birA | AL538_11420 | AL538_08720 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.758 |
| cca | dapB | AL538_11420 | AL538_11680 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.819 |
| cca | mgsA | AL538_11420 | AL538_23035 | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.807 |
| coaE | birA | AL538_06525 | AL538_08720 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.639 |
| coaE | mgsA | AL538_06525 | AL538_23035 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.845 |
| dapB | birA | AL538_11680 | AL538_08720 | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.736 |
| dapB | cca | AL538_11680 | AL538_11420 | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.819 |
| dapB | mgsA | AL538_11680 | AL538_23035 | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.832 |
| dapB | pcnB | AL538_11680 | AL538_06415 | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | poly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. | 0.816 |
| gldA | mgsA | AL538_15035 | AL538_23035 | Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.916 |
| gldA | yqhD | AL538_15035 | AL538_23985 | Glycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aldehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.910 |
| mgsA | AMG00077.1 | AL538_23035 | AL538_20450 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | 0.825 |
| mgsA | birA | AL538_23035 | AL538_08720 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | biotin--[acetyl-CoA-carboxylase] synthetase; Catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.670 |
| mgsA | cca | AL538_23035 | AL538_11420 | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 2',3'-cyclic phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. | 0.807 |