| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF96966.1 | acsA | AL538_04050 | AL538_08465 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.934 |
| AMF96966.1 | adhE | AL538_04050 | AL538_04550 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.958 |
| AMF96966.1 | cobB | AL538_04050 | AL538_00685 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. | 0.742 |
| AMF96966.1 | prpE | AL538_04050 | AL538_17040 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | propionate--CoA ligase; Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| AMF96966.1 | yfiQ | AL538_04050 | AL538_24265 | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.587 |
| AMF98762.1 | yfiQ | AL538_14085 | AL538_24265 | AMP-fatty acid ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.427 |
| AMG00540.1 | yfiQ | AL538_22950 | AL538_24265 | acetoacetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.498 |
| AMG00794.1 | AMG00795.1 | AL538_24270 | AL538_24275 | Cytochrome C biogenesis protein CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine--D-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
| AMG00794.1 | yfiQ | AL538_24270 | AL538_24265 | Cytochrome C biogenesis protein CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.573 |
| AMG00795.1 | AMG00794.1 | AL538_24275 | AL538_24270 | D-alanine--D-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cytochrome C biogenesis protein CcdA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
| AMG00795.1 | yfiQ | AL538_24275 | AL538_24265 | D-alanine--D-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.475 |
| acsA | AMF96966.1 | AL538_08465 | AL538_04050 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| acsA | adhE | AL538_08465 | AL538_04550 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| acsA | prpE | AL538_08465 | AL538_17040 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | propionate--CoA ligase; Catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.911 |
| acsA | yfiQ | AL538_08465 | AL538_24265 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.528 |
| adhE | AMF96966.1 | AL538_04550 | AL538_04050 | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.958 |
| adhE | acsA | AL538_04550 | AL538_08465 | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.921 |
| adhE | yfiQ | AL538_04550 | AL538_24265 | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Protein acetyltransferase; Catalyzes the acetylation of lysine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.485 |
| cobB | AMF96966.1 | AL538_00685 | AL538_04050 | NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. | Catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.742 |
| cobB | nnrE | AL538_00685 | AL538_26050 | NAD-dependent deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sirtuin family. Class III subfamily. | Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...] | 0.437 |