| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF99213.1 | nrdG | AL538_16505 | AL538_24430 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.832 |
| AMF99628.1 | folE | AL538_18040 | AL538_26095 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
| AMF99628.1 | nrdG | AL538_18040 | AL538_24430 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.806 |
| AMF99628.1 | queC | AL538_18040 | AL538_17070 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.876 |
| AMF99628.1 | queF | AL538_18040 | AL538_12960 | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.841 |
| QueD | folE | AL538_03020 | AL538_26095 | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
| QueD | guaA | AL538_03020 | AL538_12450 | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.628 |
| QueD | nrdG | AL538_03020 | AL538_24430 | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.814 |
| QueD | queC | AL538_03020 | AL538_17070 | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.989 |
| QueD | queF | AL538_03020 | AL538_12960 | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.943 |
| folE | AMF99628.1 | AL538_26095 | AL538_18040 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-pyruvoyl tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.775 |
| folE | QueD | AL538_26095 | AL538_03020 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
| folE | guaA | AL538_26095 | AL538_12450 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.522 |
| folE | nrdD | AL538_26095 | AL538_24435 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anaerobic ribonucleoside triphosphate reductase; Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.800 |
| folE | nrdG | AL538_26095 | AL538_24430 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.543 |
| folE | queC | AL538_26095 | AL538_17070 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.892 |
| folE | queF | AL538_26095 | AL538_12960 | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | NADPH-dependent 7-cyano-7-deazaguanine reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.825 |
| guaA | QueD | AL538_12450 | AL538_03020 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 6-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.628 |
| guaA | folE | AL538_12450 | AL538_26095 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Type I GTP cyclohydrolase I FolE; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| guaA | nrdG | AL538_12450 | AL538_24430 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.486 |