| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMF97232.1 | AMG00845.1 | AL538_05455 | AL538_24540 | UDP pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.498 |
| AMF97232.1 | fni | AL538_05455 | AL538_21100 | UDP pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.421 |
| AMF97232.1 | ispB | AL538_05455 | AL538_11150 | UDP pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.962 |
| AMF97488.1 | AMG00845.1 | AL538_06860 | AL538_24540 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.689 |
| AMF97488.1 | ispB | AL538_06860 | AL538_11150 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.403 |
| AMF97488.1 | ubiH | AL538_06860 | AL538_06865 | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.779 |
| AMG00845.1 | AMF97232.1 | AL538_24540 | AL538_05455 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.498 |
| AMG00845.1 | AMF97488.1 | AL538_24540 | AL538_06860 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-octaprenylphenol hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.689 |
| AMG00845.1 | fni | AL538_24540 | AL538_21100 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.508 |
| AMG00845.1 | glyA | AL538_24540 | AL538_13035 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.516 |
| AMG00845.1 | glyA-2 | AL538_24540 | AL538_23870 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.516 |
| AMG00845.1 | ispB | AL538_24540 | AL538_11150 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. | 0.561 |
| AMG00845.1 | menA | AL538_24540 | AL538_10785 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.838 |
| AMG00845.1 | thrS | AL538_24540 | AL538_02130 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). | 0.482 |
| AMG00845.1 | ubiF | AL538_24540 | AL538_13130 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.644 |
| AMG00845.1 | ubiH | AL538_24540 | AL538_06865 | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-octaprenyl-6-methoxyphenyl hydroxylase; Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.644 |
| fni | AMF97232.1 | AL538_21100 | AL538_05455 | Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | UDP pyrophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.421 |
| fni | AMG00845.1 | AL538_21100 | AL538_24540 | Type 2 isopentenyl-diphosphate Delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.508 |
| glyA | AMG00845.1 | AL538_13035 | AL538_24540 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 3-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.516 |
| glyA | glyA-2 | AL538_13035 | AL538_23870 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.902 |