STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iscUFe-S cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (131 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase used in synthesis of Fe-S cluster; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 0.999
hscB
Fe-S protein assembly co-chaperone; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.999
fdx
Ferredoxin, 2Fe-2S type, ISC system; COG0633 Ferredoxin.
  
 0.999
iscA
Fe-S cluster assembly protein; Belongs to the HesB/IscA family.
  
  
 0.994
hscA
Fe-S protein assembly chaperone; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.961
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.889
erpA
Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters.
  
  
 0.842
AGS07044.1
Hypothetical protein; COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes.
   
 
 0.825
dipP
COG3321 Polyketide synthase modules and related proteins; Belongs to the enoyl-CoA hydratase/isomerase family.
  
  
 0.696
AGS06957.1
Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
  
  
 0.694
Your Current Organism:
Profftella armatura
NCBI taxonomy Id: 669502
Other names: C. Profftella armatura, Candidatus Profftella armatura, syncytium symbiont of Diaphorina citri
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.