| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGS06754.1 | AGS07063.1 | SSDC_00295 | SSDC_01895 | COG0524 Sugar kinases, ribokinase family. | Phosphopyruvate hydratase; COG0148 Enolase. | 0.694 |
| AGS06754.1 | fumA | SSDC_00295 | SSDC_01725 | COG0524 Sugar kinases, ribokinase family. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.515 |
| AGS06754.1 | maeB | SSDC_00295 | SSDC_01390 | COG0524 Sugar kinases, ribokinase family. | COG0281 Malic enzyme. | 0.947 |
| AGS06754.1 | rpiAn | SSDC_00295 | SSDC_01420 | COG0524 Sugar kinases, ribokinase family. | COG0120 Ribose 5-phosphate isomerase. | 0.609 |
| AGS07063.1 | AGS06754.1 | SSDC_01895 | SSDC_00295 | Phosphopyruvate hydratase; COG0148 Enolase. | COG0524 Sugar kinases, ribokinase family. | 0.694 |
| AGS07063.1 | folD | SSDC_01895 | SSDC_00745 | Phosphopyruvate hydratase; COG0148 Enolase. | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.450 |
| AGS07063.1 | fumA | SSDC_01895 | SSDC_01725 | Phosphopyruvate hydratase; COG0148 Enolase. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.813 |
| AGS07063.1 | maeB | SSDC_01895 | SSDC_01390 | Phosphopyruvate hydratase; COG0148 Enolase. | COG0281 Malic enzyme. | 0.960 |
| AGS07063.1 | odhL | SSDC_01895 | SSDC_00435 | Phosphopyruvate hydratase; COG0148 Enolase. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.737 |
| AGS07063.1 | rlmB | SSDC_01895 | SSDC_01425 | Phosphopyruvate hydratase; COG0148 Enolase. | tRNA/rRNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.893 |
| AGS07063.1 | rpiAn | SSDC_01895 | SSDC_01420 | Phosphopyruvate hydratase; COG0148 Enolase. | COG0120 Ribose 5-phosphate isomerase. | 0.591 |
| AGS07063.1 | sucD | SSDC_01895 | SSDC_01770 | Phosphopyruvate hydratase; COG0148 Enolase. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.601 |
| folD | AGS07063.1 | SSDC_00745 | SSDC_01895 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Phosphopyruvate hydratase; COG0148 Enolase. | 0.450 |
| folD | fumA | SSDC_00745 | SSDC_01725 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.677 |
| folD | maeB | SSDC_00745 | SSDC_01390 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | COG0281 Malic enzyme. | 0.942 |
| folD | odhL | SSDC_00745 | SSDC_00435 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. | 0.519 |
| folD | rlmB | SSDC_00745 | SSDC_01425 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | tRNA/rRNA methyltransferase; COG0566 rRNA methylases; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.428 |
| folD | rpiAn | SSDC_00745 | SSDC_01420 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | COG0120 Ribose 5-phosphate isomerase. | 0.523 |
| folD | sucD | SSDC_00745 | SSDC_01770 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.510 |
| folD | trmE | SSDC_00745 | SSDC_01555 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.403 |