| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGS06861.1 | AGS07009.1 | SSDC_00850 | SSDC_01625 | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT. | 0.420 |
| AGS06861.1 | dnaJ | SSDC_00850 | SSDC_01120 | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.445 |
| AGS06861.1 | erpA | SSDC_00850 | SSDC_01505 | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | 0.945 |
| AGS06861.1 | hscB | SSDC_00850 | SSDC_00045 | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Fe-S protein assembly co-chaperone; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.928 |
| AGS06861.1 | iscU | SSDC_00850 | SSDC_00035 | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Fe-S cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.594 |
| AGS06861.1 | prfA | SSDC_00850 | SSDC_00950 | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.412 |
| AGS07009.1 | AGS06861.1 | SSDC_01625 | SSDC_00850 | Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT. | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.420 |
| AGS07009.1 | erpA | SSDC_01625 | SSDC_01505 | Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT. | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | 0.601 |
| AGS07009.1 | iscS | SSDC_01625 | SSDC_00030 | Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT. | Cysteine desulfurase used in synthesis of Fe-S cluster; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.441 |
| AGS07009.1 | iscU | SSDC_01625 | SSDC_00035 | Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT. | Fe-S cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.446 |
| dnaJ | AGS06861.1 | SSDC_01120 | SSDC_00850 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.445 |
| dnaJ | erpA | SSDC_01120 | SSDC_01505 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | 0.502 |
| dnaJ | hscA | SSDC_01120 | SSDC_00050 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Fe-S protein assembly chaperone; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family. | 0.999 |
| dnaJ | hscB | SSDC_01120 | SSDC_00045 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Fe-S protein assembly co-chaperone; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.459 |
| dnaJ | iscU | SSDC_01120 | SSDC_00035 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | Fe-S cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.575 |
| dnaJ | nuoI | SSDC_01120 | SSDC_00605 | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.661 |
| erpA | AGS06861.1 | SSDC_01505 | SSDC_00850 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.945 |
| erpA | AGS07009.1 | SSDC_01505 | SSDC_01625 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT. | 0.601 |
| erpA | dnaJ | SSDC_01505 | SSDC_01120 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.502 |
| erpA | fdx | SSDC_01505 | SSDC_00055 | Iron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. | Ferredoxin, 2Fe-2S type, ISC system; COG0633 Ferredoxin. | 0.636 |