Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters. (118 aa)    
Predicted Functional Partners:
iscU
Fe-S cluster assembly scaffold protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.921
iscS
Cysteine desulfurase used in synthesis of Fe-S cluster; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
  
 
 0.880
AGS07009.1
Glycine cleavage T protein; COG0354 Predicted aminomethyltransferase related to GcvT.
  
 
 0.788
fdx
Ferredoxin, 2Fe-2S type, ISC system; COG0633 Ferredoxin.
  
 0.757
hscB
Fe-S protein assembly co-chaperone; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.740
AGS06861.1
COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 0.729
nuoI
NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
  
 0.540
hscA
Fe-S protein assembly chaperone; COG0443 Molecular chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.511
sdhB
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.462
hisS
COG0124 Histidyl-tRNA synthetase.
     
 0.454
Your Current Organism:
Profftella armatura
NCBI taxonomy Id: 669502
Other names: C. Profftella armatura, Candidatus Profftella armatura, syncytium symbiont of Diaphorina citri
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