close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lwal_0079Mevalonate diphosphate decarboxylase. (316 aa)    
Predicted Functional Partners:
Lwal_0080
Putative mevalonate kinase.
 
  
 0.984
fni
Isopentenyl pyrophosphate isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.974
idi
Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).
 
 
 0.954
Lwal_1198
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 0.927
IspA
Geranyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
 0.927
Lwal_2673
Mevalonate kinase.
 
  
 0.924
mvaA_1
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.845
mvaA_2
Hydroxymethylglutaryl CoA reductase; Belongs to the HMG-CoA reductase family.
 
  
 0.814
Lwal_0067
Hypothetical protein.
  
  
 0.769
pal
Peptidoglycan-associated lipoprotein precursor (19 kDa surface antigen) (PPL); Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
       0.756
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.