korA protein (Legionella waltersii) - STRING interaction network

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Score

korA

2-oxoglutarate ferredoxin oxidoreductase subunit alpha. (605 aa)

Predicted Functional Partners:

Lwal_0128

0.999

nuoI

0.962

sucC

0.959

sucD

0.959

ppsA

0.955

pta_1

0.955

Lwal_1045

0.955

pta_2

0.955

acsB

0.955

pykA

0.953

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lwal_0128	Lwal_1045	Lwal_0128	Lwal_1045	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Ferredoxin II (4Fe-4S); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	0.585
Lwal_0128	acsB	Lwal_0128	Lwal_2357	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	0.915
Lwal_0128	korA	Lwal_0128	Lwal_0129	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.999
Lwal_0128	nuoI	Lwal_0128	Lwal_1979	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.	0.557
Lwal_0128	ppsA	Lwal_0128	Lwal_0272	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.	0.934
Lwal_0128	pta_1	Lwal_0128	Lwal_0488	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	0.943
Lwal_0128	pta_2	Lwal_0128	Lwal_1393	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	0.943
Lwal_0128	pykA	Lwal_0128	Lwal_2368	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Pyruvate kinase II; Belongs to the pyruvate kinase family.	0.933
Lwal_0128	sucC	Lwal_0128	Lwal_2613	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.943
Lwal_0128	sucD	Lwal_0128	Lwal_2614	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.939
Lwal_1045	Lwal_0128	Lwal_1045	Lwal_0128	Ferredoxin II (4Fe-4S); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.585
Lwal_1045	korA	Lwal_1045	Lwal_0129	Ferredoxin II (4Fe-4S); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.955
Lwal_1045	sucD	Lwal_1045	Lwal_2614	Ferredoxin II (4Fe-4S); Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.409
acsB	Lwal_0128	Lwal_2357	Lwal_0128	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.915
acsB	korA	Lwal_2357	Lwal_0129	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	0.955
acsB	pta_1	Lwal_2357	Lwal_0488	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	0.960
acsB	pta_2	Lwal_2357	Lwal_1393	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.	0.960
acsB	sucC	Lwal_2357	Lwal_2613	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.850
acsB	sucD	Lwal_2357	Lwal_2614	Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.843
korA	Lwal_0128	Lwal_0129	Lwal_0128	2-oxoglutarate ferredoxin oxidoreductase subunit alpha.	2-oxoglutarate ferredoxin oxidoreductase beta subunit.	0.999