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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lwal_0144Hypothetical protein. (106 aa)    
Predicted Functional Partners:
Lwal_0143
Hypothetical protein.
  
    0.805
Lwal_0142
Hypothetical protein.
       0.800
lspJ
Type II secretory pathway protein LspJ.
  
 
 0.642
mltA_1
Membrane-bound lytic murein transglycosylase; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.
       0.575
comA
DNA uptake/competence protein ComA.
  
  
 0.558
lspK
Type II secretory pathway protein.
  
 
 0.549
hisC-2
Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.548
phs
Pterin 4 alpha carbinolamine dehydratase.
       0.509
lspE_1
Type II protein secretion ATPase LspE.
  
 
 0.458
lspE_2
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
 
 0.458
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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