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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SfpPhosphopantetheine-protein transferase; Belongs to the P-Pant transferase superfamily. (245 aa)    
Predicted Functional Partners:
EryA
Polyketide synthase module.
 
 0.993
PpsE
Polyketide synthase, type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.991
pksJ
Polyketide synthase, type I.
 
 0.989
TycC
Peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
 
 
 0.919
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
     
 0.905
Lwal_2663
Saframycin Mx1 synthetase B.
 
 
 0.903
fabD
Malonyl CoA-ACP transacylase.
  
  
 0.849
birA
biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
       0.820
fabI_1
enoyl-ACP reductase.
  
    0.774
fabI_2
enoyl-ACP reductase.
  
    0.774
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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