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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctpA_1Cation efflux transporter. (896 aa)    
Predicted Functional Partners:
cebC
Chemiosmotic efflux system B protein C.
  
    0.800
cebB
Chemiosmotic efflux system B protein B; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
       0.800
CusA_1
Chemiosmotic efflux system B protein A; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
    0.738
Lwal_1599
Hypothetical protein; Belongs to the UPF0276 family.
   
    0.619
EryA
Polyketide synthase module.
  
 
 0.600
SapB
Putative Mg(2+) transport ATPase.
  
 
 0.565
Lwal_2663
Saframycin Mx1 synthetase B.
  
 
 0.549
pta_1
Bifunctional enoyl-CoA hydratase/phosphate acetyltransferase.
  
  
 0.541
Lwal_1597
Signal peptide protein.
   
    0.524
ack_1
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
    0.518
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: medium (48%) [HD]
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