Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
luxRTranscriptional regulator LuxR. (224 aa)    
Predicted Functional Partners:
gacS/letS
Transmission sensor LetS.
  
 
 0.852
Gmr_3
Regulatory protein (GGDEF domain).
  
 
 0.722
Cph2_6
Inner membrane protein.
  
 
 0.722
Gmr_4
GGDEF domain-containing sensory box protein.
  
 
 0.722
Lwal_0698
Glycogen synthase.
 
   
 0.620
EryA
Polyketide synthase module.
  
  
 0.618
Lwal_2663
Saframycin Mx1 synthetase B.
   
  
 0.614
Lwal_0696
3',5'-cyclic-nucleotide phosphodiesterase.
       0.524
UvrY
Response regulator GacA.
  
 
 0.474
Cph2_4
Sensory box protein.
   
 
 0.443
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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