pyrH protein (Legionella waltersii) - STRING interaction network

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Score

pyrH

Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (246 aa)

Predicted Functional Partners:

frr

0.994

tsf

0.993

rpsB

0.982

upp

0.968

pyrF

0.944

surE

0.942

ndk

0.939

Udk_2

0.925

udk

0.925

Lwal_0106

0.900

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Lwal_0106	Udk_2	Lwal_0106	Lwal_1949	ecto-ATP diphosphohydrolase II.	Uridine kinase; Belongs to the uridine kinase family.	0.900
Lwal_0106	ndk	Lwal_0106	Lwal_3089	ecto-ATP diphosphohydrolase II.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.900
Lwal_0106	pyrF	Lwal_0106	Lwal_0753	ecto-ATP diphosphohydrolase II.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.900
Lwal_0106	pyrH	Lwal_0106	Lwal_0722	ecto-ATP diphosphohydrolase II.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.900
Lwal_0106	surE	Lwal_0106	Lwal_0873	ecto-ATP diphosphohydrolase II.	Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.900
Lwal_0106	udk	Lwal_0106	Lwal_3298	ecto-ATP diphosphohydrolase II.	Uridine kinase.	0.900
Lwal_0106	upp	Lwal_0106	Lwal_2714	ecto-ATP diphosphohydrolase II.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.900
Udk_2	Lwal_0106	Lwal_1949	Lwal_0106	Uridine kinase; Belongs to the uridine kinase family.	ecto-ATP diphosphohydrolase II.	0.900
Udk_2	pyrF	Lwal_1949	Lwal_0753	Uridine kinase; Belongs to the uridine kinase family.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.914
Udk_2	pyrH	Lwal_1949	Lwal_0722	Uridine kinase; Belongs to the uridine kinase family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.925
Udk_2	surE	Lwal_1949	Lwal_0873	Uridine kinase; Belongs to the uridine kinase family.	Stationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.	0.905
Udk_2	udk	Lwal_1949	Lwal_3298	Uridine kinase; Belongs to the uridine kinase family.	Uridine kinase.	0.916
Udk_2	upp	Lwal_1949	Lwal_2714	Uridine kinase; Belongs to the uridine kinase family.	Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.	0.996
frr	ndk	Lwal_0721	Lwal_3089	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	0.875
frr	pyrH	Lwal_0721	Lwal_0722	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.994
frr	rpsB	Lwal_0721	Lwal_0724	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.	0.998
frr	tsf	Lwal_0721	Lwal_0723	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Translation elongation factor Ts (EF-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.996
ndk	Lwal_0106	Lwal_3089	Lwal_0106	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	ecto-ATP diphosphohydrolase II.	0.900
ndk	frr	Lwal_3089	Lwal_0721	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	0.875
ndk	pyrH	Lwal_3089	Lwal_0722	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.	Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.	0.939