Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CpxASensor histidine kinase CpxA. (458 aa)    
Predicted Functional Partners:
cpxR
Transcriptional regulatory protein CpxR.
 
 0.996
YbeZ
Phosphate starvation-inducible protein PhoH.
 
  
 0.906
ybeY
Metal dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
  
  
 0.892
CorC
Mg2+ and Co2+ transporter CorC.
       0.865
gacS/letS
Transmission sensor LetS.
 
 
 
0.850
lrpR
DNA-binding response regulator.
 
 
 0.772
Gmr_3
Regulatory protein (GGDEF domain).
  
 
 0.756
Cph2_6
Inner membrane protein.
  
 
 0.756
Gmr_4
GGDEF domain-containing sensory box protein.
  
 
 0.756
Lwal_0737
Hypothetical protein.
       0.743
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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