Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lssD_1Secretion system protein D. (442 aa)    
Predicted Functional Partners:
PrsD
Toxin secretion ATP binding protein.
 
  
 0.966
ApxIB_2
Toxin secretion ATP binding protein.
 
 
 0.923
BepC
Agglutination protein.
 
 
 0.865
rtxA-1
Structural toxin protein RtxA.
 
  
 0.845
rtxA_2
Structural toxin protein RtxA.
 
  
 0.763
HlyB
Toxin secretion ABC transporter ATP-binding protein.
 
 
 0.720
ApxIB_1
ABC transporter.
 
 
 0.720
SunT
Hypothetical protein; ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain.
 
 
 0.720
Lwal_0293
Periplasmic protein.
 
  
 0.587
TolC_2
Outer membrane protein TolC.
 
 
 0.548
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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