| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EryA | Lwal_2663 | Lwal_0942 | Lwal_2663 | Polyketide synthase module. | Saframycin Mx1 synthetase B. | 0.999 |
| EryA | ispB | Lwal_0942 | Lwal_1323 | Polyketide synthase module. | Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family. | 0.479 |
| EryA | ubiA | Lwal_0942 | Lwal_0747 | Polyketide synthase module. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.785 |
| EryA | ubiC | Lwal_0942 | Lwal_0748 | Polyketide synthase module. | 4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.434 |
| EryA | ubiG_2 | Lwal_0942 | Lwal_0707 | Polyketide synthase module. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.440 |
| EryA | ubiH_1 | Lwal_0942 | Lwal_2259 | Polyketide synthase module. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.528 |
| EryA | ubiH_2 | Lwal_0942 | Lwal_2260 | Polyketide synthase module. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.511 |
| Lwal_0749 | ubiA | Lwal_0749 | Lwal_0747 | Tfp type 4 fimbrial pilin like signal peptide protein domain protein. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.777 |
| Lwal_0749 | ubiC | Lwal_0749 | Lwal_0748 | Tfp type 4 fimbrial pilin like signal peptide protein domain protein. | 4-hydroxybenzoate synthetase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.777 |
| Lwal_2663 | EryA | Lwal_2663 | Lwal_0942 | Saframycin Mx1 synthetase B. | Polyketide synthase module. | 0.999 |
| Lwal_2663 | ubiA | Lwal_2663 | Lwal_0747 | Saframycin Mx1 synthetase B. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.612 |
| Lwal_2663 | ubiG_2 | Lwal_2663 | Lwal_0707 | Saframycin Mx1 synthetase B. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.447 |
| ispB | EryA | Lwal_1323 | Lwal_0942 | Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family. | Polyketide synthase module. | 0.479 |
| ispB | ubiA | Lwal_1323 | Lwal_0747 | Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.868 |
| ispB | ubiG_2 | Lwal_1323 | Lwal_0707 | Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.467 |
| ispB | ubiH_1 | Lwal_1323 | Lwal_2259 | Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.448 |
| ispB | ubiH_2 | Lwal_1323 | Lwal_2260 | Octaprenyl diphosphate synthase IspB; Belongs to the FPP/GGPP synthase family. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.426 |
| ubiA | EryA | Lwal_0747 | Lwal_0942 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Polyketide synthase module. | 0.785 |
| ubiA | Lwal_0749 | Lwal_0747 | Lwal_0749 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Tfp type 4 fimbrial pilin like signal peptide protein domain protein. | 0.777 |
| ubiA | Lwal_2663 | Lwal_0747 | Lwal_2663 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Saframycin Mx1 synthetase B. | 0.612 |