Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
pilZ_1Type 4 fimbrial biogenesis protein PilZ. (113 aa)    
Predicted Functional Partners:
Gmr_3
Regulatory protein (GGDEF domain).
    
 
 0.892
Cph2_6
Inner membrane protein.
    
 
 0.892
Gmr_4
GGDEF domain-containing sensory box protein.
    
 
 0.892
CsrD
Two component histidine kinase.
    
   0.876
Cph2_5
Inner membrane protein.
    
   0.876
YcfH
Deoxyribonuclease TatD.
  
    0.875
pilM
Tfp pilus assembly protein, ATPase PilM.
  
   
 0.867
pilN
Tfp pilus assembly protein PilN.
  
   
 0.837
Lwal_0401
Type IV pilus biogenesis protein PilP.
  
   
 0.837
Lwal_0400
Type IV pilus biogenesis protein PilO.
  
   
 0.834
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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