| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EryA | Lwal_2663 | Lwal_0942 | Lwal_2663 | Polyketide synthase module. | Saframycin Mx1 synthetase B. | 0.999 |
| EryA | acpP_1 | Lwal_0942 | Lwal_0781 | Polyketide synthase module. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.963 |
| EryA | bioH | Lwal_0942 | Lwal_3162 | Polyketide synthase module. | Biotin biosynthesis protein BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.913 |
| EryA | fabD | Lwal_0942 | Lwal_0783 | Polyketide synthase module. | Malonyl CoA-ACP transacylase. | 0.999 |
| EryA | fabF_1 | Lwal_0942 | Lwal_0780 | Polyketide synthase module. | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.981 |
| EryA | fabZ | Lwal_0942 | Lwal_2536 | Polyketide synthase module. | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.950 |
| EryA | nuoC | Lwal_0942 | Lwal_1985 | Polyketide synthase module. | NADH dehydrogenase I chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.983 |
| EryA | rplM | Lwal_0942 | Lwal_1380 | Polyketide synthase module. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.971 |
| EryA | rplU | Lwal_0942 | Lwal_1319 | Polyketide synthase module. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.979 |
| EryA | rpmF | Lwal_0942 | Lwal_0786 | Polyketide synthase module. | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.861 |
| Lwal_2663 | EryA | Lwal_2663 | Lwal_0942 | Saframycin Mx1 synthetase B. | Polyketide synthase module. | 0.999 |
| Lwal_2663 | acpP_1 | Lwal_2663 | Lwal_0781 | Saframycin Mx1 synthetase B. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.989 |
| Lwal_2663 | bioH | Lwal_2663 | Lwal_3162 | Saframycin Mx1 synthetase B. | Biotin biosynthesis protein BioH; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.730 |
| Lwal_2663 | fabD | Lwal_2663 | Lwal_0783 | Saframycin Mx1 synthetase B. | Malonyl CoA-ACP transacylase. | 0.988 |
| Lwal_2663 | fabF_1 | Lwal_2663 | Lwal_0780 | Saframycin Mx1 synthetase B. | 3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.865 |
| Lwal_2663 | fabZ | Lwal_2663 | Lwal_2536 | Saframycin Mx1 synthetase B. | (3R)-hydroxymyristoyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. | 0.758 |
| Lwal_2663 | nuoC | Lwal_2663 | Lwal_1985 | Saframycin Mx1 synthetase B. | NADH dehydrogenase I chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 30 kDa subunit family. | 0.913 |
| Lwal_2663 | rplM | Lwal_2663 | Lwal_1380 | Saframycin Mx1 synthetase B. | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.965 |
| Lwal_2663 | rplU | Lwal_2663 | Lwal_1319 | Saframycin Mx1 synthetase B. | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.962 |
| Lwal_2663 | rpmF | Lwal_2663 | Lwal_0786 | Saframycin Mx1 synthetase B. | 50S ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family. | 0.758 |