Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DtpA_2POT family transporter protein proton/peptide symporter. (491 aa)    
Predicted Functional Partners:
rsfS
Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
       0.803
rlmH
rRNA large subunit methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.748
mrdA
Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
       0.655
rodA
Rod shape-determining protein rodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
       0.655
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
     
 0.508
hutH
Histidine ammonia lyase.
  
    0.502
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
       0.497
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.497
CalB
Alcohol dehydrogenase; Belongs to the aldehyde dehydrogenase family.
       0.497
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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