Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mltDMembrane bound lytic murein transglycosylase D. (430 aa)    
Predicted Functional Partners:
flgG
Flagellar basal body rod protein FlgG; Belongs to the flagella basal body rod proteins family.
  
 
 0.793
Lwal_2485
Protein IcmE (DotG).
   
 
 0.753
rlpA_1
Lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
  
 0.695
amiB
N-acetylmuramoyl-L-alanine amidase.
  
  
 0.666
FlgJ
Muramidase, peptidoglycan hydrolase FlgJ.
     
 0.632
Lwal_0256
Methyltransferase.
  
  
 0.621
gloB
Hydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
       0.590
rlmJ
Protein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA.
       0.549
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.531
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.527
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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