Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AfrOxidoreductase. (326 aa)    
Predicted Functional Partners:
EryA
Polyketide synthase module.
  
 0.868
iolCB
IolC/IolB transferase kinase protein.
 
  
 0.819
iolG_1
Myo-inositol-2-dehydrogenase.
 
  
 0.774
Lwal_0256
Methyltransferase.
  
 
 0.740
YtbE
D-xylose reductase III.
 
 
 0.677
ytbE
Aldo/keto reductase-like diketogulonate reductase.
 
 
 0.676
iolE
Myo-inositol catabolism protein iolE.
 
  
 0.668
lysU
Lysine tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
    0.660
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
  
  
 0.627
iolD
Myo-inositol catabolism protein IolD; Belongs to the TPP enzyme family.
 
  
 0.623
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: medium (42%) [HD]