TyrA protein (Legionella waltersii) - STRING interaction network

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Score

TyrA

2-methylcitrate synthase. (355 aa)

Predicted Functional Partners:

aroC

0.998

hisC-2

0.993

hisC

0.993

aroA

0.990

trpE

0.978

aroF

0.962

aroB

0.960

serC

0.952

dhs1

0.939

aatA

0.931

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
TyrA	aatA	Lwal_1012	Lwal_2266	2-methylcitrate synthase.	Aspartate aminotransferase A.	0.931
TyrA	aroA	Lwal_1012	Lwal_0759	2-methylcitrate synthase.	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	0.990
TyrA	aroB	Lwal_1012	Lwal_0404	2-methylcitrate synthase.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	0.960
TyrA	aroC	Lwal_1012	Lwal_1228	2-methylcitrate synthase.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.998
TyrA	aroF	Lwal_1012	Lwal_1011	2-methylcitrate synthase.	Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).	0.962
TyrA	dhs1	Lwal_1012	Lwal_0552	2-methylcitrate synthase.	2-keto-3-deoxy-D-arabino-heptulosonate 7- phosphate synthase.	0.939
TyrA	hisC	Lwal_1012	Lwal_0431	2-methylcitrate synthase.	Histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase).	0.993
TyrA	hisC-2	Lwal_1012	Lwal_0145	2-methylcitrate synthase.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.993
TyrA	serC	Lwal_1012	Lwal_0760	2-methylcitrate synthase.	3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.952
TyrA	trpE	Lwal_1012	Lwal_1870	2-methylcitrate synthase.	Anthranilate synthase.	0.978
aatA	TyrA	Lwal_2266	Lwal_1012	Aspartate aminotransferase A.	2-methylcitrate synthase.	0.931
aatA	hisC	Lwal_2266	Lwal_0431	Aspartate aminotransferase A.	Histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase).	0.914
aatA	hisC-2	Lwal_2266	Lwal_0145	Aspartate aminotransferase A.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.920
aroA	TyrA	Lwal_0759	Lwal_1012	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	2-methylcitrate synthase.	0.990
aroA	aroB	Lwal_0759	Lwal_0404	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).	0.966
aroA	aroC	Lwal_0759	Lwal_1228	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.	0.993
aroA	hisC	Lwal_0759	Lwal_0431	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Histidinol-phosphate aminotransferase (imidazole acetol-phosphate transaminase).	0.460
aroA	hisC-2	Lwal_0759	Lwal_0145	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.460
aroA	serC	Lwal_0759	Lwal_0760	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	3-phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.	0.964
aroA	trpE	Lwal_0759	Lwal_1870	3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.	Anthranilate synthase.	0.622