Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Lwal_1256LysM domain-containing protein. (345 aa)    
Predicted Functional Partners:
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
 
 
 0.965
Lwal_0400
Type IV pilus biogenesis protein PilO.
  
   0.887
pilN
Tfp pilus assembly protein PilN.
  
 
   0.885
pilM
Tfp pilus assembly protein, ATPase PilM.
  
 
   0.882
dprA
DNA processing enzyme DprA.
       0.865
Lwal_1258
Hypothetical protein.
       0.865
topA_1
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.791
pilZ_1
Type 4 fimbrial biogenesis protein PilZ.
  
    0.785
Lwal_0401
Type IV pilus biogenesis protein PilP.
 
     0.773
fimV
FimV protein.
  
   
 0.764
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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