close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lwal_1597Signal peptide protein. (97 aa)    
Predicted Functional Partners:
Lwal_1599
Hypothetical protein; Belongs to the UPF0276 family.
 
  
 0.991
Lwal_1598
Hypothetical protein.
 
  
 0.968
cybA
Cytochrome b561 transmembrane protein.
 
     0.801
ycel
Polyprenyl-pyrophosphate binding protein; Belongs to the UPF0312 family.
       0.800
Lwal_1600
Silver efflux pump.
 
     0.791
YlfB
Endoglucanase; Belongs to the glycosyl hydrolase 5 (cellulase A) family.
   
    0.782
YceI_2
Putative YceI-like family protein; Belongs to the UPF0312 family.
       0.781
kup_2
KUP system potassium uptake protein; Transport of potassium into the cell; Belongs to the HAK/KUP transporter (TC 2.A.72) family.
       0.707
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.566
rtxA-1
Structural toxin protein RtxA.
   
    0.534
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: low (26%) [HD]