Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HsdR_2Type-1 restriction system, restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1020 aa)    
Predicted Functional Partners:
HsdM_2
Putative type I restriction enzyme M protein.
 
  
 0.988
Lwal_1683
EcoKI restriction-modification system protein HsdS.
 
  
 0.983
Lwal_1681
Zinc metalloprotease.
 
   
 0.950
HsdM_1
Putative type I restriction enzyme M protein.
 
  
 0.830
Lwal_2441
Zinc metalloprotease.
 
   
 0.789
HsdS
ecoKI restriction-modification system protein HsdS.
 
  
 0.745
Lwal_1686
Phage repressor.
       0.710
Lwal_1685
Hypothetical protein.
       0.705
Lwal_1734
Hypothetical protein.
   
    0.699
Lwal_3254
Fic/DOC family protein.
  
    0.640
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.