minD protein (Legionella waltersii) - STRING interaction network

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Score

minD

Septum site-determining protein (cell division inhibitor). (291 aa)

Predicted Functional Partners:

minE

0.999

minC

0.998

mreC

0.811

mreD

0.794

guaA

0.639

tadA

0.581

guaB

0.577

MreB_1

0.534

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MreB_1	minC	Lwal_0278	Lwal_3084	Rod shape determining protein MreB.	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	0.572
MreB_1	minD	Lwal_0278	Lwal_1881	Rod shape determining protein MreB.	Septum site-determining protein (cell division inhibitor).	0.534
MreB_1	mreC	Lwal_0278	Lwal_0279	Rod shape determining protein MreB.	Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.	0.996
MreB_1	mreD	Lwal_0278	Lwal_0280	Rod shape determining protein MreB.	Rod shape-determining protein MreD.	0.847
guaA	guaB	Lwal_1883	Lwal_1882	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.999
guaA	minD	Lwal_1883	Lwal_1881	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Septum site-determining protein (cell division inhibitor).	0.639
guaA	minE	Lwal_1883	Lwal_1880	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.616
guaA	tadA	Lwal_1883	Lwal_1884	GMP synthase; Catalyzes the synthesis of GMP from XMP.	tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.903
guaB	guaA	Lwal_1882	Lwal_1883	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.999
guaB	minD	Lwal_1882	Lwal_1881	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Septum site-determining protein (cell division inhibitor).	0.577
guaB	minE	Lwal_1882	Lwal_1880	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.614
guaB	tadA	Lwal_1882	Lwal_1884	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.	0.813
minC	MreB_1	Lwal_3084	Lwal_0278	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape determining protein MreB.	0.572
minC	minD	Lwal_3084	Lwal_1881	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Septum site-determining protein (cell division inhibitor).	0.998
minC	minE	Lwal_3084	Lwal_1880	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Cell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.	0.842
minC	mreC	Lwal_3084	Lwal_0279	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.	0.940
minC	mreD	Lwal_3084	Lwal_0280	Septum site determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family.	Rod shape-determining protein MreD.	0.931
minD	MreB_1	Lwal_1881	Lwal_0278	Septum site-determining protein (cell division inhibitor).	Rod shape determining protein MreB.	0.534
minD	guaA	Lwal_1881	Lwal_1883	Septum site-determining protein (cell division inhibitor).	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.639
minD	guaB	Lwal_1881	Lwal_1882	Septum site-determining protein (cell division inhibitor).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.	0.577