Dus_1 protein (Legionella waltersii) - STRING interaction network

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Dus_1

tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (306 aa)

Predicted Functional Partners:

fis_1

0.653

fis_2

0.653

fis_3

0.653

proS

0.624

recJ

0.576

panC

0.572

Lwal_1903

0.550

Lwal_1904

0.550

YfdZ

0.544

Lwal_1900

0.541

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Dus_1	Lwal_1900	Lwal_1902	Lwal_1900	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Hypothetical protein.	0.541
Dus_1	Lwal_1903	Lwal_1902	Lwal_1903	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Hypothetical protein.	0.550
Dus_1	Lwal_1904	Lwal_1902	Lwal_1904	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Hypothetical protein.	0.550
Dus_1	YfdZ	Lwal_1902	Lwal_1899	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Aminotransferase.	0.544
Dus_1	fis_1	Lwal_1902	Lwal_0807	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	DNA-binding protein fis; Belongs to the transcriptional regulatory Fis family.	0.653
Dus_1	fis_2	Lwal_1902	Lwal_1865	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Fis transcriptional activator; Belongs to the transcriptional regulatory Fis family.	0.653
Dus_1	fis_3	Lwal_1902	Lwal_2620	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Global DNA-binding transcriptional dual regulator; Belongs to the transcriptional regulatory Fis family.	0.653
Dus_1	panC	Lwal_1902	Lwal_1336	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.	0.572
Dus_1	proS	Lwal_1902	Lwal_2811	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	prolyl-tRNA synthase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]	0.624
Dus_1	recJ	Lwal_1902	Lwal_1901	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	single-stranded-DNA-specific exonuclease RecJ.	0.576
Lwal_1900	Dus_1	Lwal_1900	Lwal_1902	Hypothetical protein.	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.541
Lwal_1900	YfdZ	Lwal_1900	Lwal_1899	Hypothetical protein.	Aminotransferase.	0.800
Lwal_1900	recJ	Lwal_1900	Lwal_1901	Hypothetical protein.	single-stranded-DNA-specific exonuclease RecJ.	0.800
Lwal_1903	Dus_1	Lwal_1903	Lwal_1902	Hypothetical protein.	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.550
Lwal_1903	Lwal_1904	Lwal_1903	Lwal_1904	Hypothetical protein.	Hypothetical protein.	0.773
Lwal_1904	Dus_1	Lwal_1904	Lwal_1902	Hypothetical protein.	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.550
Lwal_1904	Lwal_1903	Lwal_1904	Lwal_1903	Hypothetical protein.	Hypothetical protein.	0.773
YfdZ	Dus_1	Lwal_1899	Lwal_1902	Aminotransferase.	tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.544
YfdZ	Lwal_1900	Lwal_1899	Lwal_1900	Aminotransferase.	Hypothetical protein.	0.800
YfdZ	recJ	Lwal_1899	Lwal_1901	Aminotransferase.	single-stranded-DNA-specific exonuclease RecJ.	0.800

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