close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YtbED-xylose reductase III. (284 aa)    
Predicted Functional Partners:
ytbE
Aldo/keto reductase-like diketogulonate reductase.
 
     0.815
Afr
Oxidoreductase.
 
 
 0.745
Lwal_2023
Serine protein kinase.
   
    0.657
EryA
Polyketide synthase module.
  
 
 0.637
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.497
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.484
Lwal_1942
Hypothetical protein.
       0.470
qor
Quinone oxidoreductase.
 
  
 0.446
sodC
Superoxide dismutase [Cu-Zn] precursor; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 
 0.444
Pld1
Aldo/keto reductase.
  
 
 0.405
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: medium (48%) [HD]