Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
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Co-expression
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[Homology]
Score
Lwal_1996Chloromuconate cycloisomerase. (367 aa)    
Predicted Functional Partners:
gntT
H gluconate symporter.
 
   
 0.892
Lwal_1998
Hypothetical protein.
       0.520
Lwal_1999
Hypothetical protein.
       0.520
LdcA_1
Muramoyltetrapeptide carboxypeptidase.
 
    0.516
LdcA_2
Muramoyltetrapeptide carboxypeptidase.
 
    0.512
yhbY
Putative RNA-binding protein.
       0.509
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
    0.478
EryA
Polyketide synthase module.
  
  
 0.425
Hcr
Oxidoreductase, FAD-binding protein.
  
  
 0.400
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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