Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
grlAGlutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily. (105 aa)    
Predicted Functional Partners:
BolA
Putative regulator; Belongs to the BolA/IbaG family.
 
 
 0.914
ahpC
Alkyl hydroperoxide reductase.
  
 
 0.834
SodB
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.810
grxC
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.690
argD
Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
       0.683
erpA
Iron-sulfur cluster assembly accessory protein family protein; Required for insertion of 4Fe-4S clusters for at least IspG.
 
 0.676
ydiC
HesB family transporter protein; Belongs to the HesB/IscA family.
 
 0.652
YrbA
BolA like protein; Belongs to the BolA/IbaG family.
 
 
 
 0.621
TrxA_2
Putative thioredoxin 1; Belongs to the thioredoxin family.
   
  
 0.610
msrA
Bifunctional methionine sulfoxide reductase B/A protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
      
 0.590
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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