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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RpfGMetal dependent phosphohydrolase. (542 aa)    
Predicted Functional Partners:
fliF
Flagellar MS-ring protein; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
    0.854
Gmr_3
Regulatory protein (GGDEF domain).
 
 
 0.830
Cph2_6
Inner membrane protein.
 
 
 0.830
Gmr_4
GGDEF domain-containing sensory box protein.
 
 
 0.830
CyaA_4
Adenylate/guanylate cyclase transmembrane protein.
 
 
   0.806
fliN
Flagellar motor switch protein FliN; FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation. Belongs to the FliN/MopA/SpaO family.
   
    0.787
gacS/letS
Transmission sensor LetS.
  
 
 0.770
CyaA_2
Guanylate cyclase.
 
 
 
 0.721
cyaA
Fused adenylate cyclase/two component hybrid sensor/regulator.
 
 
 
 0.702
CyaA_3
Guanylate cyclase.
 
 
 0.700
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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