Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Lwal_2242Cytosolic IMP-GMP specific 5'-nucleotidase. (459 aa)    
Predicted Functional Partners:
vacB
Exoribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
  
   0.868
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
       0.850
rlmB
tRNA/rRNA methyltransferase; Specifically methylates the ribose of guanosine 2251 in 23S rRNA.
       0.850
Lwal_2246
Hypothetical protein.
       0.826
Lwal_2247
Dot/Icm T4SS effector.
   
   0.637
Lwal_2205
Metalloproteinase-like protein.
 
 
   0.633
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 
    0.606
Lwal_2241
Hypothetical protein.
       0.581
Lwal_0080
Putative mevalonate kinase.
  
     0.541
Lwal_2973
Hypothetical protein.
  
 
   0.536
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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