| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Lwal_2262 | PepP | Lwal_2262 | Lwal_2261 | Hypothetical protein; Belongs to the UPF0149 family. | Xaa-Pro aminopeptidase. | 0.790 |
| Lwal_2262 | ubiH_1 | Lwal_2262 | Lwal_2259 | Hypothetical protein; Belongs to the UPF0149 family. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.747 |
| Lwal_2262 | ubiH_2 | Lwal_2262 | Lwal_2260 | Hypothetical protein; Belongs to the UPF0149 family. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.777 |
| Lwal_2262 | zapA | Lwal_2262 | Lwal_2263 | Hypothetical protein; Belongs to the UPF0149 family. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.812 |
| PepP | Lwal_2262 | Lwal_2261 | Lwal_2262 | Xaa-Pro aminopeptidase. | Hypothetical protein; Belongs to the UPF0149 family. | 0.790 |
| PepP | ubiH_1 | Lwal_2261 | Lwal_2259 | Xaa-Pro aminopeptidase. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.860 |
| PepP | ubiH_2 | Lwal_2261 | Lwal_2260 | Xaa-Pro aminopeptidase. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.838 |
| PepP | zapA | Lwal_2261 | Lwal_2263 | Xaa-Pro aminopeptidase. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.654 |
| idi | ubiA | Lwal_2671 | Lwal_0747 | Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.540 |
| idi | ubiH_1 | Lwal_2671 | Lwal_2259 | Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.843 |
| idi | ubiH_2 | Lwal_2671 | Lwal_2260 | Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.846 |
| sspA | ubiH_1 | Lwal_1371 | Lwal_2259 | Stringent starvation protein A; Belongs to the GST superfamily. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.649 |
| sspA | ubiH_2 | Lwal_1371 | Lwal_2260 | Stringent starvation protein A; Belongs to the GST superfamily. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.471 |
| ubiA | idi | Lwal_0747 | Lwal_2671 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | Isopentenyl-diphosphate Delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.540 |
| ubiA | ubiD | Lwal_0747 | Lwal_2151 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family. | 0.944 |
| ubiA | ubiG_2 | Lwal_0747 | Lwal_0707 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.648 |
| ubiA | ubiH_1 | Lwal_0747 | Lwal_2259 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 2-polyprenyl-6-methoxyphenol hydroxylase. | 0.664 |
| ubiA | ubiH_2 | Lwal_0747 | Lwal_2260 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 2-octaprenyl-6-methoxyphenol hydroxylase. | 0.795 |
| ubiA | ubiX | Lwal_0747 | Lwal_2110 | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.942 |
| ubiD | ubiA | Lwal_2151 | Lwal_0747 | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Belongs to the UbiD family. | 4-hydroxybenzoate polyprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.944 |