Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
YibH_2Multidrug resistance efflux pump PmrA. (343 aa)    
Predicted Functional Partners:
OprM_1
Outer membrane efflux protein.
 
   0.929
Lwal_2296
Hypothetical protein.
  
    0.803
Lwal_2297
Hypothetical protein.
       0.803
Lwal_2295
Hypothetical protein.
       0.757
HsrA
MFS transporter DHA2 family multidrug resistance protein B; Belongs to the major facilitator superfamily.
 
 
 0.684
OprM_2
Multidrug efflux MFS outer membrane protein.
 
 
 0.637
OprM_3
Outer membrane efflux protein.
 
 
 0.637
TtgC
Outer membrane efflux protein.
 
   0.633
helC_2
HelC protein.
 
 
 0.598
BepF_3
RND multidrug efflux membrane fusion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
   
 0.597
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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