HflC protein (Legionella waltersii) - STRING interaction network

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Score

HflC

HflC protein; HflC and HflK could regulate a protease. (304 aa)

Predicted Functional Partners:

hflK

0.997

ftsH

0.978

Lwal_0289

0.719

Lwal_2518

0.661

purA

0.568

hflX

0.565

oxaA

0.546

EryA

0.535

engB

0.532

bamB

0.486

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EryA	HflC	Lwal_0942	Lwal_2520	Polyketide synthase module.	HflC protein; HflC and HflK could regulate a protease.	0.535
EryA	Lwal_0289	Lwal_0942	Lwal_0289	Polyketide synthase module.	Putative rhomboid family protein.	0.427
EryA	Lwal_2518	Lwal_0942	Lwal_2518	Polyketide synthase module.	Ankyrin repeat-containing protein.	0.962
EryA	engB	Lwal_0942	Lwal_2356	Polyketide synthase module.	Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	0.533
EryA	ftsH	Lwal_0942	Lwal_1993	Polyketide synthase module.	Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.587
EryA	hflK	Lwal_0942	Lwal_2519	Polyketide synthase module.	Protease subunit HflK; HflC and HflK could encode or regulate a protease.	0.535
EryA	purA	Lwal_0942	Lwal_2521	Polyketide synthase module.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.581
HflC	EryA	Lwal_2520	Lwal_0942	HflC protein; HflC and HflK could regulate a protease.	Polyketide synthase module.	0.535
HflC	Lwal_0289	Lwal_2520	Lwal_0289	HflC protein; HflC and HflK could regulate a protease.	Putative rhomboid family protein.	0.719
HflC	Lwal_2518	Lwal_2520	Lwal_2518	HflC protein; HflC and HflK could regulate a protease.	Ankyrin repeat-containing protein.	0.661
HflC	bamB	Lwal_2520	Lwal_3096	HflC protein; HflC and HflK could regulate a protease.	PQQ (pyrrolo quinoline) WD40-like repeat, enzyme repeat domain protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.	0.486
HflC	engB	Lwal_2520	Lwal_2356	HflC protein; HflC and HflK could regulate a protease.	Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.	0.532
HflC	ftsH	Lwal_2520	Lwal_1993	HflC protein; HflC and HflK could regulate a protease.	Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.978
HflC	hflK	Lwal_2520	Lwal_2519	HflC protein; HflC and HflK could regulate a protease.	Protease subunit HflK; HflC and HflK could encode or regulate a protease.	0.997
HflC	hflX	Lwal_2520	Lwal_2220	HflC protein; HflC and HflK could regulate a protease.	GTP binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.	0.565
HflC	oxaA	Lwal_2520	Lwal_2208	HflC protein; HflC and HflK could regulate a protease.	Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.	0.546
HflC	purA	Lwal_2520	Lwal_2521	HflC protein; HflC and HflK could regulate a protease.	Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.	0.568
Lwal_0289	EryA	Lwal_0289	Lwal_0942	Putative rhomboid family protein.	Polyketide synthase module.	0.427
Lwal_0289	HflC	Lwal_0289	Lwal_2520	Putative rhomboid family protein.	HflC protein; HflC and HflK could regulate a protease.	0.719
Lwal_0289	ftsH	Lwal_0289	Lwal_1993	Putative rhomboid family protein.	Cell division protease ftsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.728