SucA protein (Legionella waltersii) - STRING interaction network

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gene neighborhood

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Score

SucA

2-oxoglutarate dehydrogenase E1 component. (936 aa)

Predicted Functional Partners:

sucB

0.999

LpdA

0.995

sucC

0.994

Odp2

0.993

AceF

0.993

sucD

0.988

icd

0.984

sdhA_2

0.980

sdhB_2

0.980

SdhC

0.977

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AceF	LpdA	Lwal_3136	Lwal_3137	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Dihydrolipoamide dehydrogenase.	0.999
AceF	Odp2	Lwal_3136	Lwal_3077	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.924
AceF	SdhC	Lwal_3136	Lwal_2607	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Succinate dehydrogenase cytochrome b556 subunit C.	0.439
AceF	SucA	Lwal_3136	Lwal_2611	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	2-oxoglutarate dehydrogenase E1 component.	0.993
AceF	sdhA_2	Lwal_3136	Lwal_2609	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.682
AceF	sdhB_2	Lwal_3136	Lwal_2610	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Succinate dehydrogenase iron-sulfur subunit.	0.759
AceF	sucC	Lwal_3136	Lwal_2613	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.967
AceF	sucD	Lwal_3136	Lwal_2614	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.956
LpdA	AceF	Lwal_3137	Lwal_3136	Dihydrolipoamide dehydrogenase.	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.999
LpdA	Odp2	Lwal_3137	Lwal_3077	Dihydrolipoamide dehydrogenase.	Branched-chain alpha-keto acid dehydrogenase subunit E2.	0.998
LpdA	SdhC	Lwal_3137	Lwal_2607	Dihydrolipoamide dehydrogenase.	Succinate dehydrogenase cytochrome b556 subunit C.	0.414
LpdA	SucA	Lwal_3137	Lwal_2611	Dihydrolipoamide dehydrogenase.	2-oxoglutarate dehydrogenase E1 component.	0.995
LpdA	sdhA_2	Lwal_3137	Lwal_2609	Dihydrolipoamide dehydrogenase.	Succinate dehydrogenase flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.	0.532
LpdA	sdhB_2	Lwal_3137	Lwal_2610	Dihydrolipoamide dehydrogenase.	Succinate dehydrogenase iron-sulfur subunit.	0.521
LpdA	sucB	Lwal_3137	Lwal_2612	Dihydrolipoamide dehydrogenase.	Dihydrolipoamide succinyltransferase, E2 subunit; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.999
LpdA	sucC	Lwal_3137	Lwal_2613	Dihydrolipoamide dehydrogenase.	Succinyl CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.	0.516
LpdA	sucD	Lwal_3137	Lwal_2614	Dihydrolipoamide dehydrogenase.	succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.452
Odp2	AceF	Lwal_3077	Lwal_3136	Branched-chain alpha-keto acid dehydrogenase subunit E2.	Pyruvate dehydrogenase E2 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).	0.924
Odp2	LpdA	Lwal_3077	Lwal_3137	Branched-chain alpha-keto acid dehydrogenase subunit E2.	Dihydrolipoamide dehydrogenase.	0.998
Odp2	SdhC	Lwal_3077	Lwal_2607	Branched-chain alpha-keto acid dehydrogenase subunit E2.	Succinate dehydrogenase cytochrome b556 subunit C.	0.439