pieE protein (Legionella waltersii) - STRING interaction network

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Score

pieE

Substrate of the Dot/Icm secretion system. (594 aa)

Predicted Functional Partners:

rpsN

0.847

map_2

0.829

dksA

0.771

rpmB

0.727

hisI

0.670

rpmG

0.579

rpmE

0.469

YrdA

0.413

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
YrdA	pieE	Lwal_1464	Lwal_2685	Transferase.	Substrate of the Dot/Icm secretion system.	0.413
dksA	hisI	Lwal_1189	Lwal_0426	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	0.604
dksA	pieE	Lwal_1189	Lwal_2685	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Substrate of the Dot/Icm secretion system.	0.771
dksA	rpmE	Lwal_1189	Lwal_2780	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	50S ribosomal protein L31; Binds the 23S rRNA.	0.513
hisI	dksA	Lwal_0426	Lwal_1189	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.604
hisI	map_2	Lwal_0426	Lwal_1889	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.416
hisI	pieE	Lwal_0426	Lwal_2685	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	Substrate of the Dot/Icm secretion system.	0.670
hisI	rpmE	Lwal_0426	Lwal_2780	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	50S ribosomal protein L31; Binds the 23S rRNA.	0.646
map_2	hisI	Lwal_1889	Lwal_0426	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	0.416
map_2	pieE	Lwal_1889	Lwal_2685	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Substrate of the Dot/Icm secretion system.	0.829
map_2	rpsN	Lwal_1889	Lwal_2393	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	30S ribosomal protein S14.	0.981
pieE	YrdA	Lwal_2685	Lwal_1464	Substrate of the Dot/Icm secretion system.	Transferase.	0.413
pieE	dksA	Lwal_2685	Lwal_1189	Substrate of the Dot/Icm secretion system.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.771
pieE	hisI	Lwal_2685	Lwal_0426	Substrate of the Dot/Icm secretion system.	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	0.670
pieE	map_2	Lwal_2685	Lwal_1889	Substrate of the Dot/Icm secretion system.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.829
pieE	rpmB	Lwal_2685	Lwal_2515	Substrate of the Dot/Icm secretion system.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.727
pieE	rpmE	Lwal_2685	Lwal_2780	Substrate of the Dot/Icm secretion system.	50S ribosomal protein L31; Binds the 23S rRNA.	0.469
pieE	rpmG	Lwal_2685	Lwal_2514	Substrate of the Dot/Icm secretion system.	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.579
pieE	rpsN	Lwal_2685	Lwal_2393	Substrate of the Dot/Icm secretion system.	30S ribosomal protein S14.	0.847
rpmB	pieE	Lwal_2515	Lwal_2685	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	Substrate of the Dot/Icm secretion system.	0.727