pieE protein (Legionella waltersii) - STRING interaction network

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Score

pieE

Substrate of the Dot/Icm secretion system. (594 aa)

Predicted Functional Partners:

rpsN

0.847

map_2

0.792

dksA

0.787

rpmB

0.754

hisI

0.563

rpmG

0.536

rpmE

0.468

YrdA

0.406

queF

0.400

Mta

0.400

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Mta	dksA	Lwal_1061	Lwal_1189	GTP cyclohydrolase.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.400
Mta	pieE	Lwal_1061	Lwal_2685	GTP cyclohydrolase.	Substrate of the Dot/Icm secretion system.	0.400
Mta	rpmB	Lwal_1061	Lwal_2515	GTP cyclohydrolase.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.426
Mta	rpmE	Lwal_1061	Lwal_2780	GTP cyclohydrolase.	50S ribosomal protein L31; Binds the 23S rRNA.	0.486
Mta	rpmG	Lwal_1061	Lwal_2514	GTP cyclohydrolase.	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.430
YrdA	pieE	Lwal_1464	Lwal_2685	Transferase.	Substrate of the Dot/Icm secretion system.	0.406
dksA	Mta	Lwal_1189	Lwal_1061	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	GTP cyclohydrolase.	0.400
dksA	hisI	Lwal_1189	Lwal_0426	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	0.461
dksA	pieE	Lwal_1189	Lwal_2685	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	Substrate of the Dot/Icm secretion system.	0.787
dksA	queF	Lwal_1189	Lwal_0455	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	GTP cyclohydrolase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).	0.400
dksA	rpmE	Lwal_1189	Lwal_2780	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	50S ribosomal protein L31; Binds the 23S rRNA.	0.410
hisI	dksA	Lwal_0426	Lwal_1189	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	DnaK suppressor protein; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.	0.461
hisI	map_2	Lwal_0426	Lwal_1889	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.952
hisI	pieE	Lwal_0426	Lwal_2685	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	Substrate of the Dot/Icm secretion system.	0.563
hisI	rpmE	Lwal_0426	Lwal_2780	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	50S ribosomal protein L31; Binds the 23S rRNA.	0.949
map_2	hisI	Lwal_1889	Lwal_0426	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	0.952
map_2	pieE	Lwal_1889	Lwal_2685	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	Substrate of the Dot/Icm secretion system.	0.792
map_2	rpmB	Lwal_1889	Lwal_2515	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.	0.455
map_2	rpmG	Lwal_1889	Lwal_2514	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.	0.458
map_2	rpsN	Lwal_1889	Lwal_2393	Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	30S ribosomal protein S14.	0.988