| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CbpM | cbpA | Lwal_2732 | Lwal_2731 | Putative chaperone-modulator protein CbpM. | Curved DNA binding protein DnaJ. | 0.995 |
| EryA | Lwal_2663 | Lwal_0942 | Lwal_2663 | Polyketide synthase module. | Saframycin Mx1 synthetase B. | 0.999 |
| EryA | cbpA | Lwal_0942 | Lwal_2731 | Polyketide synthase module. | Curved DNA binding protein DnaJ. | 0.941 |
| EryA | dnaK | Lwal_0942 | Lwal_0550 | Polyketide synthase module. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.634 |
| EryA | grpE | Lwal_0942 | Lwal_0551 | Polyketide synthase module. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.442 |
| EryA | htpB | Lwal_0942 | Lwal_2802 | Polyketide synthase module. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.683 |
| EryA | htpG | Lwal_0942 | Lwal_0808 | Polyketide synthase module. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.697 |
| EryA | ppiB | Lwal_0942 | Lwal_1401 | Polyketide synthase module. | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.951 |
| EryA | rplC | Lwal_0942 | Lwal_2380 | Polyketide synthase module. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.953 |
| EryA | rplN | Lwal_0942 | Lwal_2390 | Polyketide synthase module. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.948 |
| Lwal_2663 | EryA | Lwal_2663 | Lwal_0942 | Saframycin Mx1 synthetase B. | Polyketide synthase module. | 0.999 |
| Lwal_2663 | cbpA | Lwal_2663 | Lwal_2731 | Saframycin Mx1 synthetase B. | Curved DNA binding protein DnaJ. | 0.922 |
| Lwal_2663 | dnaK | Lwal_2663 | Lwal_0550 | Saframycin Mx1 synthetase B. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.505 |
| Lwal_2663 | grpE | Lwal_2663 | Lwal_0551 | Saframycin Mx1 synthetase B. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.406 |
| Lwal_2663 | htpB | Lwal_2663 | Lwal_2802 | Saframycin Mx1 synthetase B. | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.534 |
| Lwal_2663 | ppiB | Lwal_2663 | Lwal_1401 | Saframycin Mx1 synthetase B. | Peptidyl-prolyl cis-trans isomerase B; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. | 0.927 |
| Lwal_2663 | rplC | Lwal_2663 | Lwal_2380 | Saframycin Mx1 synthetase B. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.937 |
| Lwal_2663 | rplN | Lwal_2663 | Lwal_2390 | Saframycin Mx1 synthetase B. | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.928 |
| cbpA | CbpM | Lwal_2731 | Lwal_2732 | Curved DNA binding protein DnaJ. | Putative chaperone-modulator protein CbpM. | 0.995 |
| cbpA | EryA | Lwal_2731 | Lwal_0942 | Curved DNA binding protein DnaJ. | Polyketide synthase module. | 0.941 |