close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FixLTwo-component sensor histidine kinase. (478 aa)    
Predicted Functional Partners:
Gmr_3
Regulatory protein (GGDEF domain).
 
 
 0.925
gacS/letS
Transmission sensor LetS.
 
 
 0.836
flgD
Flagellar basal body rod modification protein; Required for flagellar hook formation. May act as a scaffolding protein.
   
    0.766
Cph2_6
Inner membrane protein.
  
 
 0.634
Gmr_4
GGDEF domain-containing sensory box protein.
  
 
 0.634
Lwal_1706
Membrane protein.
  
     0.557
Lwal_1692
Bile acid beta-glucosidase.
  
   
 0.548
Lwal_1699
Hypothetical protein.
  
     0.548
ArcB
Sensory box sensor histidine kinase/response regulator.
 
 0.547
Lwal_2901
Membrane protein.
  
     0.547
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.