ArtJ_2 protein (Legionella waltersii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ArtJ_2

Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family. (248 aa)

Predicted Functional Partners:

ArtQ

0.922

GlnQ

0.797

GlnE

0.592

Lwal_2797

0.509

braC

0.463

Lwal_2798

0.412

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ArtJ_2	ArtQ	Lwal_2795	Lwal_1760	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	Amino acid (glutamine) ABC transporter permease.	0.922
ArtJ_2	GlnE	Lwal_2795	Lwal_2796	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	0.592
ArtJ_2	GlnQ	Lwal_2795	Lwal_1759	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	Amino acid (glutamine) ABC transporter ATP binding protein.	0.797
ArtJ_2	Lwal_2797	Lwal_2795	Lwal_2797	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	Hypothetical protein.	0.509
ArtJ_2	Lwal_2798	Lwal_2795	Lwal_2798	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	Hypothetical protein.	0.412
ArtJ_2	braC	Lwal_2795	Lwal_2424	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor.	0.463
ArtQ	ArtJ_2	Lwal_1760	Lwal_2795	Amino acid (glutamine) ABC transporter permease.	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	0.922
ArtQ	GlnQ	Lwal_1760	Lwal_1759	Amino acid (glutamine) ABC transporter permease.	Amino acid (glutamine) ABC transporter ATP binding protein.	0.999
ArtQ	braC	Lwal_1760	Lwal_2424	Amino acid (glutamine) ABC transporter permease.	Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor.	0.473
GlnE	ArtJ_2	Lwal_2796	Lwal_2795	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	0.592
GlnE	Lwal_2797	Lwal_2796	Lwal_2797	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	Hypothetical protein.	0.714
GlnE	Lwal_2798	Lwal_2796	Lwal_2798	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	Hypothetical protein.	0.564
GlnQ	ArtJ_2	Lwal_1759	Lwal_2795	Amino acid (glutamine) ABC transporter ATP binding protein.	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	0.797
GlnQ	ArtQ	Lwal_1759	Lwal_1760	Amino acid (glutamine) ABC transporter ATP binding protein.	Amino acid (glutamine) ABC transporter permease.	0.999
Lwal_2797	ArtJ_2	Lwal_2797	Lwal_2795	Hypothetical protein.	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	0.509
Lwal_2797	GlnE	Lwal_2797	Lwal_2796	Hypothetical protein.	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	0.714
Lwal_2797	Lwal_2798	Lwal_2797	Lwal_2798	Hypothetical protein.	Hypothetical protein.	0.608
Lwal_2798	ArtJ_2	Lwal_2798	Lwal_2795	Hypothetical protein.	Arginine ABC transporter substrate-binding protein; Belongs to the bacterial solute-binding protein 3 family.	0.412
Lwal_2798	GlnE	Lwal_2798	Lwal_2796	Hypothetical protein.	Adenylyl transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...]	0.564
Lwal_2798	Lwal_2797	Lwal_2798	Lwal_2797	Hypothetical protein.	Hypothetical protein.	0.608

page 1 of 2

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About