dnaJ_3 protein (Legionella waltersii) - STRING interaction network

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Score

dnaJ_3

Chaperone protein DnaJ. (347 aa)

Predicted Functional Partners:

dnaK

0.982

EryA

0.952

ftsA

0.948

ftsQ

0.945

Lwal_2663

0.925

htpG

0.915

ftsI

0.897

mrdA

0.897

rsfS

0.885

grpE

0.851

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EryA	Lwal_2663	Lwal_0942	Lwal_2663	Polyketide synthase module.	Saframycin Mx1 synthetase B.	0.999
EryA	dnaJ_3	Lwal_0942	Lwal_2861	Polyketide synthase module.	Chaperone protein DnaJ.	0.952
EryA	dnaK	Lwal_0942	Lwal_0550	Polyketide synthase module.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.634
EryA	ftsI	Lwal_0942	Lwal_0383	Polyketide synthase module.	Peptidoglycan synthetase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.423
EryA	grpE	Lwal_0942	Lwal_0551	Polyketide synthase module.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.442
EryA	htpG	Lwal_0942	Lwal_0808	Polyketide synthase module.	Heat shock protein 90; Molecular chaperone. Has ATPase activity.	0.697
EryA	mrdA	Lwal_0942	Lwal_0802	Polyketide synthase module.	Penicillin binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.418
EryA	rsfS	Lwal_0942	Lwal_0800	Polyketide synthase module.	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.719
Lwal_2663	EryA	Lwal_2663	Lwal_0942	Saframycin Mx1 synthetase B.	Polyketide synthase module.	0.999
Lwal_2663	dnaJ_3	Lwal_2663	Lwal_2861	Saframycin Mx1 synthetase B.	Chaperone protein DnaJ.	0.925
Lwal_2663	dnaK	Lwal_2663	Lwal_0550	Saframycin Mx1 synthetase B.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.505
Lwal_2663	grpE	Lwal_2663	Lwal_0551	Saframycin Mx1 synthetase B.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.406
Lwal_2663	rsfS	Lwal_2663	Lwal_0800	Saframycin Mx1 synthetase B.	Ribosomal silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.	0.715
dnaJ_3	EryA	Lwal_2861	Lwal_0942	Chaperone protein DnaJ.	Polyketide synthase module.	0.952
dnaJ_3	Lwal_2663	Lwal_2861	Lwal_2663	Chaperone protein DnaJ.	Saframycin Mx1 synthetase B.	0.925
dnaJ_3	dnaK	Lwal_2861	Lwal_0550	Chaperone protein DnaJ.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.982
dnaJ_3	ftsA	Lwal_2861	Lwal_1270	Chaperone protein DnaJ.	Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family.	0.948
dnaJ_3	ftsI	Lwal_2861	Lwal_0383	Chaperone protein DnaJ.	Peptidoglycan synthetase FtsI precursor; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.897
dnaJ_3	ftsQ	Lwal_2861	Lwal_1271	Chaperone protein DnaJ.	Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.	0.945
dnaJ_3	grpE	Lwal_2861	Lwal_0551	Chaperone protein DnaJ.	Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]	0.851