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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemL-2Glutamate-1-semialdehyde-2,1-aminomutase. (429 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 
 0.990
hemA
Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.986
TycC
Peptide synthetase; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.962
PpsE
Polyketide synthase, type I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
    
 0.949
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 
0.923
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.905
Lwal_2663
Saframycin Mx1 synthetase B.
 
 
 0.846
DipZ
Cytochrome C biogenesis protein.
  
  
 0.657
EryA
Polyketide synthase module.
 
  
 0.596
prpC
2-methylcitrate synthase; Belongs to the citrate synthase family.
  
    0.587
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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