Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilC_2Pilus assembly protein PilC. (406 aa)    
Predicted Functional Partners:
pilB
Pilus assembly protein PilB.
 
 
 0.995
OutO
Type 4 (IV) prepilin-like protein leader peptide processing enzyme PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.989
lspE_2
Type II protein secretion ATPase LspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
 
 
 0.939
lspE_1
Type II protein secretion ATPase LspE.
 
 
 0.936
uptC
Type II secretion system protein.
 
   
 0.809
pilT
Twitching motility protein PilT.
 
  
 0.806
pilM
Tfp pilus assembly protein, ATPase PilM.
 
 
 
 0.805
YggR
DotB.
 
  
 0.787
pilQ
Type IV pilus (Tfp) assembly protein PilQ.
 
 
 
 0.771
comA
DNA uptake/competence protein ComA.
  
  
 0.717
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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