mutT_2 protein (Legionella waltersii) - STRING interaction network

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Score

mutT_2

Mutator protein MutT; Belongs to the Nudix hydrolase family. (130 aa)

Predicted Functional Partners:

secA

0.800

Lwal_3175

0.529

mutY

0.456

Ada

0.448

hisI

0.441

polA

0.437

Lwal_3172

0.429

Your Current Organism:

Legionella waltersii

NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ada	mutT_2	Lwal_3022	Lwal_3173	Transcription regulator protein.	Mutator protein MutT; Belongs to the Nudix hydrolase family.	0.448
Ada	mutY	Lwal_3022	Lwal_0364	Transcription regulator protein.	A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.549
Ada	polA	Lwal_3022	Lwal_2334	Transcription regulator protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.600
Lwal_3172	mutT_2	Lwal_3172	Lwal_3173	Hypothetical protein.	Mutator protein MutT; Belongs to the Nudix hydrolase family.	0.429
Lwal_3172	secA	Lwal_3172	Lwal_3174	Hypothetical protein.	Preprotein translocase, secretion protein SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.	0.429
Lwal_3175	mutT_2	Lwal_3175	Lwal_3173	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Mutator protein MutT; Belongs to the Nudix hydrolase family.	0.529
Lwal_3175	secA	Lwal_3175	Lwal_3174	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	Preprotein translocase, secretion protein SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.	0.511
hisI	mutT_2	Lwal_0426	Lwal_3173	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	Mutator protein MutT; Belongs to the Nudix hydrolase family.	0.441
mutT_2	Ada	Lwal_3173	Lwal_3022	Mutator protein MutT; Belongs to the Nudix hydrolase family.	Transcription regulator protein.	0.448
mutT_2	Lwal_3172	Lwal_3173	Lwal_3172	Mutator protein MutT; Belongs to the Nudix hydrolase family.	Hypothetical protein.	0.429
mutT_2	Lwal_3175	Lwal_3173	Lwal_3175	Mutator protein MutT; Belongs to the Nudix hydrolase family.	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.	0.529
mutT_2	hisI	Lwal_3173	Lwal_0426	Mutator protein MutT; Belongs to the Nudix hydrolase family.	Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; In the N-terminal section; belongs to the PRA-CH family.	0.441
mutT_2	mutY	Lwal_3173	Lwal_0364	Mutator protein MutT; Belongs to the Nudix hydrolase family.	A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	0.456
mutT_2	polA	Lwal_3173	Lwal_2334	Mutator protein MutT; Belongs to the Nudix hydrolase family.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.437
mutT_2	secA	Lwal_3173	Lwal_3174	Mutator protein MutT; Belongs to the Nudix hydrolase family.	Preprotein translocase, secretion protein SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family.	0.800
mutY	Ada	Lwal_0364	Lwal_3022	A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Transcription regulator protein.	0.549
mutY	mutT_2	Lwal_0364	Lwal_3173	A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	Mutator protein MutT; Belongs to the Nudix hydrolase family.	0.456
mutY	polA	Lwal_0364	Lwal_2334	A/G specific adenine glycosylase; Adenine glycosylase active on G-A mispairs.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.473
polA	Ada	Lwal_2334	Lwal_3022	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Transcription regulator protein.	0.600
polA	mutT_2	Lwal_2334	Lwal_3173	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Mutator protein MutT; Belongs to the Nudix hydrolase family.	0.437