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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LdhA2-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)    
Predicted Functional Partners:
pykA
Pyruvate kinase II; Belongs to the pyruvate kinase family.
  
 0.933
gloB
Hydroxyacylglutathione hydrolase (glyoxalase II); Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
  
 0.914
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.912
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.905
sfcA
Malate dehydrogenase.
    
 0.903
MaeA_2
Malate dehydrogenase.
    
 0.903
mao2
Malate oxidoreductase.
    
 0.903
AceE
Pyruvate dehydrogenase E1 component oxidoreductase protein AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.903
Lwal_0128
2-oxoglutarate ferredoxin oxidoreductase beta subunit.
    
  0.902
CfiA
Oxaloacetate decarboxylase subunit alpha.
    
  0.902
Your Current Organism:
Legionella waltersii
NCBI taxonomy Id: 66969
Other names: ATCC 51914, CCUG 44924, CIP 104965, DSM 21908, L. waltersii, NCTC 13017, strain 2074-AUS-E
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